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CS-W001157 4
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2-((tert-Butoxycarbonyl)amino)-2-(3,5-dichlorophenyl)acetic acid

  • CAS No. 369403-30-5

  • Cat. No. CS-0159655
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-((tert-Butoxycarbonyl)amino)-2-(3,5-dichlorophenyl)acetic acid|CS-0159655

Structure of 369403-30-5

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General Information

  • CAS No. 369403-30-5
  • Cat. No. CS-0159655
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₅Cl₂NO₄
  • Molecular Weight 320.17
  • Synonym(s) 3,5-Dichloro-a-(Boc-amino)benzeneacetic acid
  • SMILES O=C(O)C(NC(OC(C)(C)C)=O)C1=CC(Cl)=CC(Cl)=C1

Description

This protected amino acid derivative features a tert-butoxycarbonyl group enabling stable incorporation into peptide synthesis. The 3,5-dichlorophenyl moiety imparts enhanced lipophilicity and metabolic stability, facilitating efficient conjugation in bioactive molecule design under standard conditions.

Application

2-((tert-Butoxycarbonyl)amino)-2-(3,5-dichlorophenyl)acetic acid serves as a stable, bench-ready building block for peptide and heterocyclic synthesis. The Boc-protected amine enables straightforward deprotection under mild acidic conditions, while the 3,5-dichlorophenyl group provides orthogonal reactivity and enhanced metabolic stability. Its functional group tolerance facilitates use in standard coupling protocols and multi-step sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.6438
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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