(R)-2-Amino-2-(3-chlorophenyl)acetic acid hydrochloride

Name: (R)-2-Amino-2-(3-chlorophenyl)acetic acid hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 37085-27-1
Cat. No. CS-0007842
Purity≥98%
MDL No.MFCD25977348

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-Amino-2-(3-chlorophenyl)acetic acid hydrochloride|CS-0007842

Structure of 37085-27-1

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Description

(R)-2-Amino-2-(3-chlorophenyl)acetic acid hydrochloride is a chiral building block featuring a benzylic amine and a para-chlorinated aromatic ring. This bench-stable, moisture-tolerant derivative integrates readily into peptide synthesis and pharmaceutical intermediates, offering high enantiomeric purity for asymmetric transformations.

Application

(R)-2-Amino-2-(3-chlorophenyl)acetic acid hydrochloride serves as a stereochemically defined building block for bioactive molecules, enabling efficient synthesis of chiral pharmaceutical intermediates. Its stability under standard reaction conditions and compatibility with common coupling protocols facilitate straightforward incorporation into peptidomimetics and heterocyclic scaffolds. The pendant chlorophenyl group provides a handle for further functionalization via cross-coupling or electrophilic substitution, enhancing versatility in medicinal chemistry campaigns.

General Information

CAS No. 37085-27-1
Cat. No. CS-0007842
Purity ≥98%
MDL No. MFCD25977348
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉Cl₂NO₂
Molecular Weight 222.07
Synonym(s) D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride)
SMILES ClC1=CC([C@H](C(O)=O)N)=CC=C1.Cl

Computational Chemistry Data

TPSA 63.32
LogP 1.8462
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Glycine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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(R)-2-Amino-2-(3-chlorophenyl)acetic acid hydrochloride

CAS No. 37085-27-1

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