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Structure of 371-14-2
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(4-Fluorophenyl)hydrazine is a bench-stable, electron-deficient hydrazine derivative featuring a para-fluoro substituent that enhances reactivity in azo coupling and cyclization reactions. This functional group enables efficient incorporation into heterocyclic scaffolds under mild conditions, offering improved selectivity in synthetic transformations.
(4-Fluorophenyl)hydrazine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrazoles, triazoles, and other nitrogen-rich scaffolds via cycloaddition and condensation reactions. Its fluorinated aryl group enhances metabolic stability and modulates electronic properties, making it valuable for medicinal chemistry applications. The compound exhibits good bench stability and compatibility with common functional groups, facilitating straightforward purification and integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: