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CS-W001157 4
Total: USD 88.00

4-Fluorobutan-1-ol

  • CAS No. 372-93-0

  • Cat. No. CS-0116811
  • Purity≥97%
  • MDL No.MFCD00039555

*For research and further manufacturing use only, not for direct human use.

4-Fluorobutan-1-ol|CS-0116811

Structure of 372-93-0

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General Information

  • CAS No. 372-93-0
  • Cat. No. CS-0116811
  • Purity ≥97%
  • MDL No. MFCD00039555
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉FO
  • Molecular Weight 92.11
  • Synonym(s) 4-Fluoro-1-butanol
  • SMILES OCCCCF

Description

4-Fluorobutan-1-ol is a fluorinated aliphatic alcohol featuring a terminal hydroxyl group and a fluorine atom at the γ-position. This configuration imparts enhanced metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. The molecule exhibits favorable solubility in polar solvents and serves as a key building block in the synthesis of bioactive compounds.

Application

4-Fluorobutan-1-ol serves as a versatile fluorinated building block for synthesizing bioactive molecules and functional materials. Its primary alcohol functionality enables straightforward derivatization, while the terminal fluorine imparts enhanced metabolic stability and modulated lipophilicity. The molecule exhibits good bench stability and compatibility with standard protecting group strategies, facilitating its use in multi-step syntheses involving amide formation, etherification, or coupling reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   0.7284
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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