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Structure of 3728-43-6
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Trimethyl(p-tolyl)silane features a sterically protected silicon center with a para-methyl aryl group, enhancing stability and facilitating selective functionalization. This bench-stable reagent integrates readily into cross-coupling protocols, delivering robust silane transfer under mild conditions.
Trimethyl(p-tolyl)silane serves as a stable, bench-ready silylating agent that facilitates efficient protection of alcohols and carboxylic acids under mild conditions. Its ortho-substituted aryl group enhances steric shielding and thermal stability, enabling selective transformations in complex molecule synthesis. The reagent exhibits excellent functional group tolerance and is compatible with standard purification protocols, making it a reliable choice for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: