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CS-W001157 4
Total: USD 88.00

(3-(Dimethylcarbamoyl)phenyl)boronic acid

  • CAS No. 373384-14-6

  • Cat. No. CS-W004904
  • Molecule weight193.01
  • Purity≥97%
  • MDL No.MFCD03412066

*For research and further manufacturing use only, not for direct human use.

(3-(Dimethylcarbamoyl)phenyl)boronic acid|CS-W004904

Structure of 373384-14-6

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General Information

  • CAS No. 373384-14-6
  • Cat. No. CS-W004904
  • Purity ≥97%
  • MDL No. MFCD03412066
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂BNO₃
  • Molecular Weight 193.01
  • Synonym(s) 3-(Dimethylcarbamoyl)benzeneboronic Acid (contains varying amounts of Anhydride)
  • SMILES O=C(C1=CC(B(O)O)=CC=C1)N(C)C

Description

This boronic acid features a dimethylcarbamoyl group at the meta position, enhancing solubility and stability while maintaining reactivity in Suzuki-Miyaura coupling. The electron-withdrawing carbamoyl moiety fine-tunes electrophilicity, enabling efficient cross-coupling under standard conditions.

Application

(3-(Dimethylcarbamoyl)phenyl)boronic acid serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The dimethylcarbamoyl group enhances solubility and stability while maintaining compatibility with diverse functional groups, facilitating straightforward purification and broad applicability in medicinal chemistry and materials synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   60.77
  • LogP   -0.9318
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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