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Structure of 373384-19-1
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(2-Hydroxypyrimidin-5-yl)boronic acid features a pyrimidine scaffold with a boronic acid group at the 5-position, enabling direct coupling in Suzuki-Miyaura reactions. The adjacent hydroxyl substituent enhances solubility and stabilizes the boronate through intramolecular hydrogen bonding. This combination delivers high reactivity under mild conditions while maintaining bench stability and compatibility with diverse functional groups.
(2-Hydroxypyrimidin-5-yl)boronic acid serves as a versatile building block for constructing pyrimidine-based scaffolds in medicinal chemistry and materials science. Its boronic acid functionality enables efficient Suzuki-Miyaura cross-coupling reactions under mild conditions, while the adjacent hydroxyl group enhances solubility and provides additional sites for derivatization. The compound exhibits good bench stability and is compatible with a range of functional groups, facilitating straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: