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Structure of 374064-01-4
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This pyrazole-based heterocycle integrates a pyridyl group and a carboxylic acid moiety, enabling direct conjugation in bioactive molecule design. The electron-deficient pyrazole core enhances reactivity in coupling reactions, while the carboxylic acid facilitates derivatization under standard conditions.
3-(Pyridin-3-yl)-1H-pyrazole-5-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its pyrazole-carboxylic acid motif enables facile derivatization via amide coupling, esterification, or metal-catalyzed cross-coupling reactions. The molecule exhibits good bench stability and functional group tolerance, facilitating integration into complex scaffolds. Its structural rigidity and hydrogen-bonding capacity support target engagement in biological systems, making it valuable for scaffold hopping and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: