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CS-W001157 4
Total: USD 88.00

Methyl 1H-benzo[d]imidazole-7-carboxylate

  • CAS No. 37619-25-3

  • Cat. No. CS-0007685
  • Purity≥97%
  • MDL No.MFCD09910212
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Methyl 1H-benzo[d]imidazole-7-carboxylate|CS-0007685

Structure of 37619-25-3

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Description

Methyl 1H-benzo[d]imidazole-7-carboxylate is a bench-stable heterocyclic ester featuring a fused imidazole core with a para-substituted methyl carboxylate. This compound integrates readily into synthetic sequences requiring electron-deficient aromatic platforms, serving as a key intermediate in the construction of bioactive nitrogen-containing scaffolds.

Application

Methyl 1H-benzo[d]imidazole-7-carboxylate serves as a versatile building block in medicinal chemistry and synthetic organic research. Its benzimidazole core provides a rigid, electron-rich scaffold with demonstrated utility in drug discovery. The methyl ester group enables straightforward derivatization via hydrolysis or nucleophilic substitution, facilitating access to carboxylic acid intermediates or amide-linked analogs. The compound exhibits good bench stability, moderate solubility in common organic solvents, and compatibility with standard coupling reactions, making it well-suited for modular synthesis of heterocyclic libraries and API precursors.

General Information

  • CAS No. 37619-25-3
  • Cat. No. CS-0007685
  • Purity ≥97%
  • MDL No. MFCD09910212
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂
  • Molecular Weight 176.17
  • Synonym(s) methyl 1H-benzo[d]imidazole-4-carboxylate
  • SMILES O=C(C1=C2C(N=CN2)=CC=C1)OC

Computational Chemistry Data

  • TPSA   54.98
  • LogP   1.3495
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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