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Structure of 37619-25-3
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Methyl 1H-benzo[d]imidazole-7-carboxylate is a bench-stable heterocyclic ester featuring a fused imidazole core with a para-substituted methyl carboxylate. This compound integrates readily into synthetic sequences requiring electron-deficient aromatic platforms, serving as a key intermediate in the construction of bioactive nitrogen-containing scaffolds.
Methyl 1H-benzo[d]imidazole-7-carboxylate serves as a versatile building block in medicinal chemistry and synthetic organic research. Its benzimidazole core provides a rigid, electron-rich scaffold with demonstrated utility in drug discovery. The methyl ester group enables straightforward derivatization via hydrolysis or nucleophilic substitution, facilitating access to carboxylic acid intermediates or amide-linked analogs. The compound exhibits good bench stability, moderate solubility in common organic solvents, and compatibility with standard coupling reactions, making it well-suited for modular synthesis of heterocyclic libraries and API precursors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: