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CS-W001157 4
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5-Bromo-3-methyl-2-pyridinecarbaldehyde

  • CAS No. 376587-53-0

  • Cat. No. CS-0039842
  • Purity≥97%
  • MDL No.MFCD07776420
  • HazMat Fee +

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    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-methyl-2-pyridinecarbaldehyde|CS-0039842

Structure of 376587-53-0

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Description

5-Bromo-3-methyl-2-pyridinecarbaldehyde features a brominated pyridine core with a methyl group at the 3-position and an aldehyde function at the 2-position. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key building block for bioactive heterocycles and ligand synthesis under standard conditions.

Application

5-Bromo-3-methyl-2-pyridinecarbaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to functionalized pyridine scaffolds. Its bromo and aldehyde groups provide orthogonal handles for Suzuki-Miyaura coupling, nucleophilic addition, and condensation reactions, while the methyl group enhances metabolic stability. The compound exhibits good bench stability and is compatible with standard purification techniques, facilitating its use in multi-step syntheses of bioactive molecules and API intermediates.

General Information

  • CAS No. 376587-53-0
  • Cat. No. CS-0039842
  • Purity ≥97%
  • MDL No. MFCD07776420
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO
  • Molecular Weight 200.03
  • Synonym(s) None
  • SMILES O=CC1=NC=C(Br)C=C1C

Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.96502
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P280-P304+P340-P405

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