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Structure of 37959-19-6
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This pyrazole-acetic acid derivative features a pyridinyl-substituted dihydro-1H-pyrazolone core with a pendant carboxylic acid group, enabling direct conjugation or metal chelation. The electron-deficient pyrazolone ring enhances reactivity in coupling reactions, while the benzylic-like acetic acid facilitates derivatization under mild conditions. Bench-stable and moisture-tolerant, it serves as a modular scaffold for probe synthesis.
2-[5-Oxo-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrazol-3-yl]acetic acid serves as a versatile building block for heterocyclic scaffolds, enabling efficient access to pyrazole-based pharmacophores. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the pyridinyl group enhances solubility and provides a handle for further functionalization. Bench-stable and compatible with standard purification methods, it functions effectively in medicinal chemistry campaigns targeting kinase inhibitors and other bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: