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Structure of 37972-24-0
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2-Ethynylpyrimidine delivers a reactive alkyne handle within a nitrogen-rich heterocyclic framework, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and materials functionalization. This bench-stable, moisture-tolerant reagent integrates seamlessly into modular synthesis workflows.
2-Ethynylpyrimidine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed coupling reactions such as Sonogashira and Suzuki-Miyaura transformations. Its terminal alkyne functionality exhibits excellent stability under standard reaction conditions and facilitates efficient access to functionalized pyrimidine scaffolds commonly found in pharmaceutical and agrochemical intermediates. The molecule demonstrates broad compatibility with diverse functional groups and supports straightforward purification, making it well-suited for iterative synthesis and library development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: