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Structure of 38071-22-6
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4,5-Dibromothiophene-2-carbaldehyde features a highly reactive aldehyde group flanked by bromine substituents at the 4 and 5 positions of the thiophene ring. This configuration enables direct coupling in cross-coupling reactions, offering efficient access to functionalized heterocycles. The molecule exhibits enhanced stability under standard handling conditions and integrates readily into synthetic sequences requiring electron-deficient building blocks.
4,5-Dibromothiophene-2-carbaldehyde serves as a versatile building block for the synthesis of brominated heterocyclic scaffolds and functionalized thiophene derivatives. Its dual bromine substituents enable efficient Pd-catalyzed cross-coupling reactions, while the aldehyde group facilitates imine formation, reductive amination, or oxidation to carboxylic acid. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthetic sequences in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: