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Structure of 38180-46-0
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3-Chloro-2-pyridinecarbonitrile features a chlorine atom at the 3-position and a nitrile group at the 2-position of the pyridine ring, creating a highly electron-deficient heterocyclic scaffold. This structural motif enables efficient coupling in cross-coupling reactions and serves as a key intermediate in medicinal chemistry for constructing bioactive molecules. The compound exhibits good stability under standard handling conditions and demonstrates favorable solubility in polar organic solvents.
3-Chloro-2-pyridinecarbonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of nitrogen-containing heterocycles. Its dual functional groups—electron-withdrawing chlorine and nitrile—facilitate nucleophilic substitution, palladium-catalyzed coupling, and cyclization reactions under standard conditions. The compound exhibits good bench stability and is amenable to purification via recrystallization or column chromatography, supporting reliable use in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: