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Structure of 38239-45-1
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5-Bromo-3-methylthiophene-2-carboxylic acid features a brominated thiophene core with a methyl group at the 3-position and a carboxylic acid at the 2-position, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient bromo substituent facilitates cross-coupling reactions, while the carboxylic acid group provides a versatile handle for amide formation or metal chelation. This structure offers enhanced solubility in organic media and stability under standard bench conditions, supporting efficient use in medicinal chemistry and materials synthesis workflows.
5-Bromo-3-methylthiophene-2-carboxylic acid serves as a versatile building block for the synthesis of substituted thiophenes and heterocyclic scaffolds. Its bromo and carboxylic acid functionalities enable direct coupling reactions, including Suzuki-Miyaura and Stille couplings, and facilitate derivatization via amide or ester formation. The molecule exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: