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Structure of 383-70-0
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TFA-Gly-OH is a trifluoroacetylated glycine derivative featuring a terminal hydroxyl group. This stable, moisture-tolerant reagent facilitates efficient peptide coupling under standard conditions, enabling direct incorporation of N-terminal trifluoroacetyl protection in synthetic sequences.
TFA-Gly-OH serves as a versatile building block in peptide synthesis, enabling efficient N-terminal capping and side-chain protection. Its trifluoroacetyl (TFA) group enhances solubility and stability during reaction sequences, while the C-terminal carboxylic acid facilitates straightforward coupling with amino acids or amines. The compound exhibits excellent functional group tolerance and simplifies purification through its distinct polarity profile, making it well-suited for both solid-phase and solution-phase synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: