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4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxybenzamide Metoclopramide Impurity

  • CAS No. 38339-95-6

  • Cat. No. CS-0533962
  • Purity≥98%
  • MDL No.MFCD21363709

*For research and further manufacturing use only, not for direct human use.

4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxybenzamide Metoclopramide Impurity|CS-0533962

Structure of 38339-95-6

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General Information

  • CAS No. 38339-95-6
  • Cat. No. CS-0533962
  • Purity ≥98%
  • MDL No. MFCD21363709
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₀ClN₃O₂
  • Molecular Weight 285.77
  • Synonym(s) o-Desmethyl metoclopramide
  • SMILES O=C(C1=C(O)C=C(N)C(Cl)=C1)NCCN(CC)CC

Synthesis

  • Route1

    References

    • Monkovic, Ivo; Wllner, David; Adam, Michael A.; Brown, Myron; Crenshaw, R. R.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 8 p. 1548 - 1557
  • Route2

    References

    • Bristol-Myers Company Patent: US4808624 A1, 1989 ; US 4808624 A
  • Route3
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    • 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxybenzamide Metoclopramide Impurity|CS-0533962
      38339-95-6

    References

    • Nassar; House; Agharkar Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 11 p. 1088 - 1091

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.59
  • LogP   1.6994
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   6

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