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CS-W001157 4
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4-Chloro-3-nitrocoumarin

  • CAS No. 38464-20-9

  • Cat. No. CS-0204833
  • Purity≥98%
  • MDL No.MFCD00051670

*For research and further manufacturing use only, not for direct human use.

4-Chloro-3-nitrocoumarin|CS-0204833

Structure of 38464-20-9

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General Information

  • CAS No. 38464-20-9
  • Cat. No. CS-0204833
  • Purity ≥98%
  • MDL No. MFCD00051670
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₄ClNO₄
  • Molecular Weight 225.59
  • Synonym(s) 4-Chloro-3-nitro-chromen-2-one
  • SMILES O=C1OC2=C(C(Cl)=C1[N+]([O-])=O)C=CC=C2

Description

Cbz-N-amido-PEG8-acid is a PEG linker containing a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions.

Synthesis

  • Route1

    References

    • Govori; Rapic; Leci; Cacic; Tabakovic Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 2 p. 351 - 354

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   73.35
  • LogP   2.3546
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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