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Structure of 38521-06-1
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Pyrazine-2(1H)-thione features a fused heterocyclic core with a labile thione group, enabling direct coordination to transition metals and facilitating use in catalytic systems. This electron-deficient scaffold integrates readily into functionalized ligands and exhibits enhanced reactivity under mild conditions.
Pyrazine-2(1H)-thione serves as a versatile heterocyclic building block for medicinal chemistry and materials science, enabling efficient access to pyrazine-based scaffolds via nucleophilic substitution, metal-catalyzed coupling, and cyclization reactions. Its thione functionality offers enhanced reactivity in transition-metal-mediated transformations while maintaining bench stability and compatibility with common protecting groups. The compound facilitates the construction of complex nitrogen-rich architectures under standard synthetic conditions.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: