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CS-W001157 4
Total: USD 88.00

1-(4-Nitrophenyl)piperidin-2-one Apixaban Impurity 64

  • CAS No. 38560-30-4

  • Cat. No. CS-M0372
  • Purity≥98%
  • MDL No.MFCD04037154

*For research and further manufacturing use only, not for direct human use.

1-(4-Nitrophenyl)piperidin-2-one Apixaban Impurity 64|CS-M0372

Structure of 38560-30-4

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General Information

  • CAS No. 38560-30-4
  • Cat. No. CS-M0372
  • Purity ≥98%
  • MDL No. MFCD04037154
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂N₂O₃
  • Molecular Weight 220.23
  • Synonym(s) 1-(4-Nitrophenyl)Piperidin-2-One
  • SMILES O=C1N(C2=CC=C(C=C2)N(=O)=O)CCCC1

Synthesis

  • Route1
    • In-stock
      5-Bromopentanoyl chloride|CS-0083325
      4509-90-4
    • null|null
      100-01-6
    • ~95%
    • In-stock
      1-(4-Nitrophenyl)piperidin-2-one Apixaban Impurity 64|CS-M0372
      38560-30-4

    References

    • Pinto, Donald J.P.; Han, Wei; Hu, Zilun; Qiao, Jennifer Patent: US2003/232804 A1, 2003 ; Location in patent: Page 102 ;
  • Route2

    References

    • Pinto, Donald J. P.; Orwat, Michael J.; Koch, Stephanie; Rossi, Karen A.; Alexander, Richard S.; Smallwood, Angela; Wong, Paneras C.; Rendina, Alan R.; Luettgen, Joseph M.; Knabb, Robert M.; He, Kan; Xin, Baomin; Wexler, Ruth R.; Lam, Patrick Y. S. Journal of Medicinal Chemistry, 2007 , vol. 50, # 22 p. 5339 - 5356
  • Route3

    References

    • Jiang, Jian'An; Ji, Yafei Synthetic Communications, 2013 , vol. 43, # 1 p. 72 - 79

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.45
  • LogP   2.1117
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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