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Structure of 38980-96-0
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4-(Trifluoromethyl)benzimidamide hydrochloride features a trifluoromethyl group that imparts enhanced lipophilicity and metabolic stability, while the imidamide moiety provides a robust hydrogen-bonding scaffold. This combination enables efficient integration into bioactive scaffolds for medicinal chemistry applications.
4-(Trifluoromethyl)benzimidamide hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its trifluoromethyl group enhances metabolic stability and membrane permeability, while the amide functionality supports diverse downstream transformations. The hydrochloride salt ensures excellent bench stability and ease of handling, facilitating straightforward purification and incorporation into coupling reactions or scaffold elaboration workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: