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CS-W001157 4
Total: USD 88.00

O-(2-(vinyloxy)ethyl)hydroxylamine

  • CAS No. 391212-29-6

  • Cat. No. CS-M0262
  • Molecule weight103.12
  • Purity≥96%
  • MDL No.MFCD09951926

*For research and further manufacturing use only, not for direct human use.

O-(2-(vinyloxy)ethyl)hydroxylamine|CS-M0262

Structure of 391212-29-6

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General Information

  • CAS No. 391212-29-6
  • Cat. No. CS-M0262
  • Purity ≥96%
  • MDL No. MFCD09951926
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO₂
  • Molecular Weight 103.12
  • Synonym(s) Selumetinib Intermediate
  • SMILES NOCCOC=C

Description

O-(2-(Vinyloxy)ethyl)hydroxylamine integrates a reactive vinyloxy group with a hydroxylamine moiety, enabling efficient conjugation in polymer functionalization and bioconjugate chemistry. This bench-stable reagent facilitates site-specific labeling under mild conditions.

Application

O-(2-(Vinyloxy)ethyl)hydroxylamine serves as a versatile building block for the synthesis of nitrogen-containing heterocycles and functionalized polymers. Its pendant vinyl group enables facile radical or transition-metal-catalyzed coupling reactions, while the hydroxylamine moiety offers controlled reactivity in oxime formation and N-oxidation processes. The compound exhibits good bench stability and compatibility with common protecting group strategies, facilitating its use in multi-step synthetic sequences requiring selective functionalization.

Synthesis

  • Route1
    • 2-(2-(vinyloxy)ethoxy)isoindoline-1,3-dione|CS-M0261
      391212-30-9
    • ~77%
    • In-stock
      O-(2-(vinyloxy)ethyl)hydroxylamine|CS-M0262
      391212-29-6

    References

    • CHEMIZON, A DIVISION OF OPTOMAGIC CO., LTD. Patent: US2012/238599 A1, 2012 ; Location in patent: Page/Page column 19 ; US 20120238599 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅱ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   0.0368
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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