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CS-W001157 4
Total: USD 88.00

3-Bromooxetane

  • CAS No. 39267-79-3

  • Cat. No. CS-D1251
  • Purity≥98%
  • MDL No.MFCD08544402
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Bromooxetane|CS-D1251

Structure of 39267-79-3

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Description

3-Bromooxetane is a strained, reactive three-membered cyclic ether bearing a bromine substituent at the 3-position. This configuration imparts high ring strain and facilitates regioselective ring-opening under mild conditions, enabling efficient incorporation into complex molecular architectures. The bromine moiety serves as a versatile handle for downstream functionalization via cross-coupling or nucleophilic substitution reactions.

Application

3-Bromooxetane serves as a versatile, bench-stable building block for the construction of oxetane-containing scaffolds in medicinal chemistry. Its strained three-membered ring enables efficient nucleophilic substitution and transition-metal-catalyzed coupling reactions, facilitating rapid access to bioactive molecules. The bromine atom provides a reliable handle for diversification via cross-coupling, enabling incorporation into complex pharmaceutical intermediates with high functional group tolerance and predictable reactivity.

General Information

  • CAS No. 39267-79-3
  • Cat. No. CS-D1251
  • Purity ≥98%
  • MDL No. MFCD08544402
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅BrO
  • Molecular Weight 136.98
  • Synonym(s) Oxetane, 3-bromo-
  • SMILES BrC1COC1

Computational Chemistry Data

  • TPSA   9.23
  • LogP   0.7801
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P330-P370+P378-P501

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