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Structure of 393568-74-6
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Boc-D-His(Trt)-OH features a protected D-histidine residue with a trifluoromethylcarbamoyl (Trt) group on the imidazole nitrogen and a tert-butoxycarbonyl (Boc) group on the α-amino terminus. This configuration enables stable incorporation into peptide chains under standard coupling conditions, facilitating efficient synthesis of D-configured histidine-containing sequences with minimal side reactions.
Boc-D-His(Trt)-OH serves as a protected amino acid building block for the synthesis of peptide analogs and heterocyclic scaffolds. The Trt (trityl) group provides orthogonal protection of the imidazole nitrogen, enabling selective functionalization during solid-phase synthesis. The Boc group ensures stability under basic conditions and facilitates straightforward deprotection with mild acid. This derivative exhibits excellent bench stability and compatibility with standard coupling protocols, making it a reliable choice for complex peptide and medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: