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Structure of 3939-12-6
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5-Cyano-2-fluoropyridine features a strategically positioned cyano group and fluorine atom on the pyridine ring, enabling enhanced reactivity in cross-coupling processes. The electron-deficient aromatic core facilitates efficient nucleophilic substitution, while the bench-stable nature supports reliable handling under standard conditions.
5-Cyano-2-fluoropyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the 3-position via nucleophilic substitution due to the ortho-fluoro activation. Its dual electron-withdrawing groups (cyano and fluoro) enhance reactivity in cross-coupling reactions and facilitate the construction of substituted pyridine scaffolds common in pharmaceuticals. The compound exhibits good bench stability and is compatible with standard purification methods.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: