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CS-W001157 4
Total: USD 88.00

5-Bromonicotinoyl chloride

  • CAS No. 39620-02-5

  • Cat. No. CS-0695440
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromonicotinoyl chloride|CS-0695440

Structure of 39620-02-5

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Description

5-Bromonicotinoyl chloride is a reactive acylating agent featuring a brominated pyridine ring, enabling efficient incorporation into complex molecular architectures. The compound exhibits high electrophilicity at the carbonyl center, facilitating rapid amide bond formation under mild conditions. This reactivity, combined with its stability during storage and ease of handling, makes it ideal for synthesizing bioactive heterocycles and functionalized intermediates in medicinal chemistry workflows.

Application

5-Bromonicotinoyl chloride serves as a versatile acylating agent for the synthesis of brominated nicotinamide derivatives and heterocyclic scaffolds. Its reactivity enables efficient amide bond formation under mild conditions, with good functional group tolerance and bench stability. The bromine substituent provides a handle for subsequent cross-coupling reactions, facilitating access to complex pharmaceutical intermediates and agrochemical building blocks.

General Information

  • CAS No. 39620-02-5
  • Cat. No. CS-0695440
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClNO
  • Molecular Weight 220.45
  • Synonym(s) None
  • SMILES ClC(=O)C1=CC(Br)=CN=C1

Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2923
Class : 8 (6.1)
Packing Group : Ⅲ
Hazard Statements : H301-H311-H314-H331
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P403+P233-P405-P501

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