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CS-W001157 4
Total: USD 88.00

5-Bromo-3-pyridylacetic acid

  • CAS No. 39891-12-8

  • Cat. No. CS-W014873
  • Purity≥95%
  • MDL No.MFCD00829308

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-pyridylacetic acid|CS-W014873

Structure of 39891-12-8

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General Information

  • CAS No. 39891-12-8
  • Cat. No. CS-W014873
  • Purity ≥95%
  • MDL No. MFCD00829308
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₂
  • Molecular Weight 216.03
  • Synonym(s) 5-Bromo-3-pyridineacetic acid
  • SMILES OC(=O)CC1=CC(Br)=CN=C1

Description

5-Bromo-3-pyridylacetic acid features a brominated pyridine ring linked to a carboxylic acid-bearing acetic side chain, enabling direct incorporation into bioactive molecule scaffolds. The electron-deficient pyridine core enhances reactivity in cross-coupling and functionalization reactions, while the pendant carboxyl group provides a handle for amide bond formation or metal chelation. This structure supports synthetic access to pharmaceutical intermediates and ligands requiring halogenated heterocyclic motifs under standard conditions.

Application

5-Bromo-3-pyridylacetic acid serves as a versatile building block for constructing bioactive heterocycles and pharmaceutical intermediates. Its brominated pyridine core enables efficient Pd-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates direct derivatization or amidation. The compound exhibits good bench stability and compatibility with standard synthetic workflows, enabling straightforward incorporation into complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.4712
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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