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Structure of 399-88-2
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3-Fluoro-4-methylpyridine features a fluorinated pyridine core with a methyl group at the 4-position, delivering enhanced electronic modulation and improved metabolic stability. This bench-stable heterocycle integrates readily into medicinal chemistry scaffolds, serving as a key building block for kinase inhibitors and bioactive small molecules.
3-Fluoro-4-methylpyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine ring due to its ortho-fluoro activation. The methyl group provides a handle for oxidation or selective substitution, while the fluorine facilitates nucleophilic aromatic substitution under mild conditions. Its stability and compatibility with common coupling reactions make it a practical choice for constructing heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: