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CS-W001157 4
Total: USD 88.00

1-Methyl-4-nitro-1H-pyrazole

  • CAS No. 3994-50-1

  • Cat. No. CS-W002627
  • Purity≥98%
  • MDL No.MFCD00464261
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

1-Methyl-4-nitro-1H-pyrazole|CS-W002627

Structure of 3994-50-1

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Description

1-Methyl-4-nitro-1H-pyrazole is a bench-stable heterocyclic compound featuring a nitro group at the para position relative to a methyl-substituted nitrogen. This electron-deficient pyrazole integrates readily into synthetic sequences requiring polar, reactive intermediates. Its stability under standard conditions enables straightforward handling in process development workflows.

Application

1-Methyl-4-nitro-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling efficient construction of nitrogen-rich heterocycles. Its nitro group facilitates reduction to an amine, which can be further elaborated via coupling or cyclization reactions. The molecule exhibits bench stability and compatibility with common functional groups, simplifying purification and integration into multi-step syntheses.

General Information

  • CAS No. 3994-50-1
  • Cat. No. CS-W002627
  • Purity ≥98%
  • MDL No. MFCD00464261
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅N₃O₂
  • Molecular Weight 127.10
  • Synonym(s) 1H-Pyrazole, 1-methyl-4-nitro-
  • SMILES Cn1ncc(c1)[N+](=O)[O-]

Computational Chemistry Data

  • TPSA   60.96
  • LogP   0.3283
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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