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CS-W001157 4
Total: USD 88.00

Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate

  • CAS No. 39945-51-2

  • Cat. No. CS-W012658
  • Purity≥96%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate|CS-W012658

Structure of 39945-51-2

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Description

Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate features a piperidine core bearing a hydroxymethyl group and a benzyl ester, enabling facile deprotection and functionalization. This scaffold integrates readily into complex molecular architectures, offering controlled access to amine-functionalized intermediates under standard conditions.

Application

Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to piperidine-based scaffolds. The benzyloxycarbonyl (Cbz) group provides stable protection under standard conditions, while the primary hydroxymethyl functionality facilitates selective derivatization via oxidation, etherification, or substitution reactions. Its bench-stable nature and compatibility with common coupling protocols make it ideal for multi-step synthesis of bioactive molecules and API intermediates.

General Information

  • CAS No. 39945-51-2
  • Cat. No. CS-W012658
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉NO₃
  • Molecular Weight 249.31
  • Synonym(s) N-Cbz-3-hydroxymethylpiperidine
  • SMILES O=C(N1CC(CO)CCC1)OCC2=CC=CC=C2

Computational Chemistry Data

  • TPSA   49.77
  • LogP   2.0275
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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