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Structure of 39974-94-2
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5-Methoxy-1-methyl-1H-indole-3-carbaldehyde features a benzene-fused indole core with a methoxy group at the 5-position and a methyl substituent at nitrogen, delivering enhanced solubility and metabolic stability. The aldehyde functionality at C3 enables direct coupling in Ullmann or reductive amination reactions. This electron-rich scaffold serves as a key building block for bioactive heterocycles and fluorescent probes.
5-Methoxy-1-methyl-1H-indole-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted indole scaffolds. The aldehyde group facilitates reductive amination, Grignard additions, and Ugi-type couplings, while the methoxy and methyl substituents provide orthogonal functional handles for further derivatization. Its bench-stable nature and compatibility with standard purification methods make it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: