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Structure of 4002-83-9
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1-Methyl-1H-indazole-3-carbaldehyde features a conjugated aldehyde group fused to a nitrogen-rich heterocycle, enabling direct integration into Suzuki and Ugi-type coupling cascades. The methyl substituent enhances solubility and modulates electronic properties, while the indazole scaffold provides metabolic stability and favorable binding geometry in kinase-targeted drug discovery.
1-Methyl-1H-indazole-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the aldehyde position for imine formation, reductive amination, or Grignard additions. Its indazole core provides metabolic stability and favorable π-stacking interactions, while the methyl group enhances solubility and reduces susceptibility to oxidation. The aldehyde functionality offers high reactivity in standard coupling protocols, facilitating rapid access to diverse heterocyclic scaffolds and drug-like molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: