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Structure of 400755-43-3
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1-Ethyl-1H-pyrazole-5-carboxylic acid features a pyrazole core with complementary electron-rich and carboxylic acid functionalities, enabling direct integration into bioconjugation and medicinal chemistry scaffolds. The ethyl substituent enhances solubility and metabolic stability in aqueous systems, while the para-carboxylic acid group provides a reactive handle for amide coupling or derivatization under standard conditions.
1-Ethyl-1H-pyrazole-5-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrazole-based scaffolds in medicinal chemistry and agrochemical development. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The ethyl group enhances solubility and metabolic stability, while the pyrazole core provides robust structural rigidity and hydrogen-bonding capacity. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: