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Structure of 401-79-6
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1-Methyl-3-(trifluoromethyl)benzene features a trifluoromethyl group flanking a methyl substituent on a benzene ring, delivering enhanced electron-withdrawing character and improved metabolic stability. This structural motif enables efficient incorporation into pharmaceutical intermediates and agrochemical scaffolds under standard conditions.
1-Methyl-3-(trifluoromethyl)benzene serves as a valuable aryl building block in medicinal chemistry and agrochemical synthesis, offering enhanced lipophilicity and metabolic stability due to the electron-withdrawing trifluoromethyl group. Its bench-stable nature and compatibility with standard cross-coupling reactions facilitate efficient functionalization at the aromatic ring.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: