8-Bromoguanosine

Name: 8-Bromoguanosine
Brand: ChemScene
Availability: InStock
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CAS No. 4016-63-1
Cat. No. CS-W020382
Molecule weight362.14
Purity≥97%
MDL No.MFCD00037985

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 4016-63-1

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General Information

CAS No. 4016-63-1
Cat. No. CS-W020382
Purity ≥97%
MDL No. MFCD00037985
Storage -20°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₂BrN₅O₅
Molecular Weight 362.14
Synonym(s) None
SMILES OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(Br)=NC3=C2N=C(N)NC3=O)O1

Description

8-Bromoguanosine is a purine nucleoside analog featuring a bromine atom at the C8 position, conferring enhanced stability and altered base-pairing properties. This modification facilitates its use in probing RNA structure and function, particularly in studies involving enzymatic recognition and conformational dynamics. The compound integrates readily into oligonucleotides and serves as a valuable tool for site-specific labeling and structural interrogation in biochemical assays.

Synthesis

Route1
- In-stock
  
  118-00-3
- ~91%
- In-stock
  
  4016-63-1
References
- Baranowski, Daniel; Golankiewicz, Bozenna; Folkman, Wojciech; Popenda, Mariusz Nucleosides, Nucleotides and Nucleic Acids, 2012 , vol. 31, # 10 p. 707 - 719
Route2
- 15717-45-0
- ~92%
- In-stock
  
  4016-63-1
References
- Meier, Lidiane; Monteiro, Gustavo C.; Baldissera, Rodrigo A.M.; Sa, Marcus Mandolesi Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 859 - 866

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 159.51
LogP -1.9242
H_Acceptors 9
H_Donors 5
Rotatable_Bonds 2

Other Classifications

Life Science Nucleosides & Nucleotides 5'-Protected Nucleosides

Chemical Biology Nucleic Acid Chemistry Protected Nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

Key Words

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8-Bromoguanosine

CAS No. 4016-63-1

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