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Structure of 401629-04-7
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5-Cyclopropyl-1H-pyrazole-3-carboxylic acid features a cyclopropyl group at the 5-position, enhancing lipophilicity and metabolic stability. The carboxylic acid moiety enables direct derivatization or salt formation. This scaffold integrates readily into bioactive molecules, particularly in kinase inhibitor and CNS-targeted compound libraries.
5-Cyclopropyl-1H-pyrazole-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its pyrazole core provides robust stability and moderate lipophilicity, while the carboxylic acid functionality enables direct derivatization via amide coupling, esterification, or salt formation. The cyclopropyl group enhances metabolic stability and contributes to favorable pharmacokinetic properties in bioactive scaffolds. This compound demonstrates excellent bench stability and compatibility with standard purification methods, facilitating integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: