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Structure of 401816-16-8
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This boronate moiety features a difluoropyridine scaffold, delivering enhanced stability and tunable reactivity in cross-coupling processes. The electron-deficient pyridine ring facilitates efficient palladium-catalyzed transformations, while the fluorine substituents improve solubility and metabolic resistance. Ideal for constructing bioactive heterocycles under standard conditions.
(2,6-Difluoropyridin-4-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The strategically positioned fluorine substituents enhance reactivity through electronic activation while maintaining bench stability and compatibility with diverse functional groups. Its predictable coupling behavior and ease of purification make it well-suited for iterative synthesis in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: