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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-cyanophenyl)propanoic acid

  • CAS No. 401933-16-2

  • Cat. No. CS-0067113
  • Molecule weight412.44
  • Purity≥95%
  • MDL No.MFCD01863771

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-cyanophenyl)propanoic acid|CS-0067113

Structure of 401933-16-2

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General Information

  • CAS No. 401933-16-2
  • Cat. No. CS-0067113
  • Purity ≥95%
  • MDL No. MFCD01863771
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₀N₂O₄
  • Molecular Weight 412.44
  • Synonym(s) Fmoc-L-2-Cyanophenylalanine
  • SMILES O=C(O)[C@H](CC1=CC=CC=C1C#N)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-cyanophenyl)propanoic acid is a chiral building block featuring a fluorenylmethoxycarbonyl (Fmoc) protected amino group and a para-cyano-substituted phenyl side chain. This configuration enables direct incorporation into peptide synthesis workflows, where the Fmoc group facilitates orthogonal deprotection under mild basic conditions. The electron-withdrawing nitrile enhances reactivity in coupling reactions, while the sterically defined chiral center ensures high enantioselectivity in downstream applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   99.42
  • LogP   4.09268
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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