Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Methylpicolinic acid

  • CAS No. 4021-08-3

  • Cat. No. CS-W005037
  • Purity≥98%
  • MDL No.MFCD03731175

*For research and further manufacturing use only, not for direct human use.

4-Methylpicolinic acid|CS-W005037

Structure of 4021-08-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4021-08-3
  • Cat. No. CS-W005037
  • Purity ≥98%
  • MDL No. MFCD03731175
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₂
  • Molecular Weight None
  • Synonym(s) 4-Methyl-Pyridine-2-Carboxylic Acid
  • SMILES CC1=CC=NC(=C1)C(=O)O

Description

4-Methylpicolinic acid features a methyl-substituted pyridine ring that enhances electron density at the nitrogen, improving coordination in metal complexes. This bench-stable carboxylic acid integrates readily into ligand frameworks for catalysis and materials science applications.

Application

4-Methylpicolinic acid serves as a versatile building block in medicinal chemistry and catalysis, offering a robust pyridine scaffold with enhanced electron density at the ortho position. Its carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation, while the methyl group provides a handle for further functionalization. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for use in standard synthetic workflows targeting heterocyclic APIs and metal-chelating ligands.

Synthesis

  • Route1

    References

    • THE UNIVERSITY OF WARWICK Patent: WO2008/17855 A1, 2008 ; Location in patent: Page/Page column 49 ;
  • Route2
    • 2-(Bromomethyl)-4-methylpyridine|CS-0665441
      442910-29-4
    • ~79%
    • In-stock
      4-Methylpicolinic acid|CS-W005037
      4021-08-3

    References

    • Zhong, Qi-Di; Xue, Yun-Zhou; Yan, Hong; Song, Xiu-Qing; Zhong, Ru-Gang Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 18 p. 5532 - 5535
  • Route3
    • null|null
      108-47-4
    • ~10%
    • In-stock
      2-Methylisonicotinic acid|CS-W008764
      4021-11-8
    • In-stock
      4-Methylpicolinic acid|CS-W005037
      4021-08-3

    References

    • Angewandte Chemie, , vol. 104, # 6 p. 748 - 749

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P264-P280-P305+P351+P338-P337+P313

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.08822
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Methylpicolinic acid sigma4-Methylpicolinic acid manufacturer4-Methylpicolinic acid price4-Methylpicolinic acid structure4-Methylpicolinic acid SDSbuy 4-Methylpicolinic acid4-Methylpicolinic acid supplier4-Methylpicolinic acid uses4-Methylpicolinic acid molecular weightprice of 4-Methylpicolinic acid4-Methylpicolinic acid chemical name formula of 4-Methylpicolinic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label