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Structure of 40222-77-3
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2-Hydroxymethyl-5-hydroxypyridine features a pyridine core functionalized with hydroxyl and hydroxymethyl groups at the 5- and 2-positions, respectively. This arrangement enables dual hydrogen-bonding capacity and facilitates integration into chelating ligands or bioactive scaffolds. The compound exhibits enhanced solubility in polar solvents and stability under standard bench conditions, supporting its utility in medicinal chemistry and catalyst design.
2-Hydroxymethyl-5-hydroxypyridine serves as a versatile pyridine-based building block for medicinal chemistry and agrochemical synthesis. The molecule features two hydroxyl groups in ortho relationship to the nitrogen atom, enabling facile derivatization via etherification, esterification, or metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with common protecting group strategies facilitate efficient route optimization. Functions effectively in the construction of heterocyclic scaffolds and bioactive intermediates requiring polar, hydrogen-bonding functionality.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: