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Structure of 403-45-2
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6-Fluoronicotinic acid is a bench-stable, electron-deficient heterocyclic carboxylic acid featuring a fluorine atom at the 6-position of the pyridine ring. This strategic substitution enhances its utility in synthetic routes requiring directed functionalization, particularly in pharmaceutical intermediates and bioactive molecule design.
6-Fluoronicotinic acid serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocycles and bioactive scaffolds. Its ortho-fluoro substitution enhances metabolic stability and modulates electronic properties, while the carboxylic acid functionality facilitates direct derivatization or coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic transformations, making it a practical choice for API development and library synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: