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Structure of 40430-66-8
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1-Ethynyladamantane offers a rigid, sterically encumbered alkyne handle ideal for copper-catalyzed click chemistry and bioconjugation. The adamantane scaffold imparts exceptional stability and lipophilicity, enhancing membrane permeability and metabolic resistance in probe design. This robust molecular framework integrates seamlessly into complex architectures without compromising structural integrity.
1-Ethynyladamantane serves as a robust, bench-stable building block for CuAAC and Sonogashira coupling reactions. Its rigid adamantane scaffold imparts exceptional stability and enhances solubility in organic media, enabling efficient incorporation into complex molecular architectures. The terminal alkyne functionality facilitates reliable conjugation with azides and palladium-catalyzed cross-couplings, making it a valuable reagent for constructing functionalized scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: