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CS-W001157 4
Total: USD 88.00

Pyrrolidin-3-ol

  • CAS No. 40499-83-0

  • Cat. No. CS-W022946
  • Molecule weight87.12
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Pyrrolidin-3-ol|CS-W022946

Structure of 40499-83-0

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General Information

  • CAS No. 40499-83-0
  • Cat. No. CS-W022946
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO
  • Molecular Weight 87.12
  • Synonym(s) Pyrrolidine-3-ol
  • SMILES OC1CNCC1

Description

Pyrrolidin-3-ol features a saturated five-membered ring with a hydroxyl group at the 3-position, conferring enhanced solubility and hydrogen-bonding capacity. This polar scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for modulating pharmacokinetic properties.

Application

Pyrrolidin-3-ol serves as a versatile building block in medicinal chemistry, enabling the construction of saturated heterocycles with well-documented utility in bioactive molecule synthesis. Its hydroxyl group provides a handle for derivatization, while the nitrogen atom offers moderate basicity and hydrogen-bonding capacity. The compound exhibits good bench stability and compatibility with common functional groups, facilitating its use in multi-step syntheses, including peptide mimetics and kinase inhibitor scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.6594
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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