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Structure of 405-79-8
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4-Fluorophenoxyacetic acid features a fluorinated aromatic ring paired with a carboxylic acid handle, enabling robust integration into bioactive molecule scaffolds. This bench-stable derivative offers enhanced metabolic stability and improved membrane permeability compared to non-fluorinated analogs, making it valuable for medicinal chemistry campaigns targeting CNS-penetrant compounds.
4-Fluorophenoxyacetic acid serves as a versatile building block in medicinal chemistry, enabling the incorporation of both phenolic and carboxylic acid functionalities into target molecules. Its fluorinated aromatic ring enhances metabolic stability and modulates electronic properties, while the pendant acetic acid group facilitates conjugation via amide, ester, or salt formation. The compound exhibits good bench stability and is compatible with standard synthetic protocols, making it well-suited for the construction of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: