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CS-W001157 4
Total: USD 88.00

(5-Bromo-6-chloro-pyridin-3-yl)-carbamic acid tert-butyl ester

  • CAS No. 405939-59-5

  • Cat. No. CS-0340352
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Bromo-6-chloro-pyridin-3-yl)-carbamic acid tert-butyl ester|CS-0340352

Structure of 405939-59-5

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General Information

  • CAS No. 405939-59-5
  • Cat. No. CS-0340352
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂BrClN₂O₂
  • Molecular Weight 307.57
  • Synonym(s) tert-Butyl (5-bromo-6-chloropyridin-3-yl)carbamate
  • SMILES CC(C)(OC(NC1=CC(Br)=C(N=C1)Cl)=O)C

Synthesis

  • Route1

    References

    • Kuo, Gee-Hong; Prouty, Catherine; Wang, Aihua; Emanuel, Stuart; DeAngelis, Alan; Zhang, Yan; Song, Fengbin; Beall, Lawrence; Connolly, Peter J.; Karnachi, Prahba; Chen, Xin; Gruninger, Robert H.; Sechler, Jan; Fuentes-Pesquera, Angel; Middleton, Steven A.; Jolliffe, Linda; Murray, William V. Journal of Medicinal Chemistry, 2005 , vol. 48, # 15 p. 4892 - 4909
  • Route2
    • 6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520
      5006-66-6
    • ~%
    • (5-Bromo-6-chloro-pyridin-3-yl)-carbamic acid tert-butyl ester|CS-0340352
      405939-59-5

    References

    • Kuo, Gee-Hong; Prouty, Catherine; Wang, Aihua; Emanuel, Stuart; DeAngelis, Alan; Zhang, Yan; Song, Fengbin; Beall, Lawrence; Connolly, Peter J.; Karnachi, Prahba; Chen, Xin; Gruninger, Robert H.; Sechler, Jan; Fuentes-Pesquera, Angel; Middleton, Steven A.; Jolliffe, Linda; Murray, William V. Journal of Medicinal Chemistry, 2005 , vol. 48, # 15 p. 4892 - 4909
  • Route3

    References

    • Kuo, Gee-Hong; Prouty, Catherine; Wang, Aihua; Emanuel, Stuart; DeAngelis, Alan; Zhang, Yan; Song, Fengbin; Beall, Lawrence; Connolly, Peter J.; Karnachi, Prahba; Chen, Xin; Gruninger, Robert H.; Sechler, Jan; Fuentes-Pesquera, Angel; Middleton, Steven A.; Jolliffe, Linda; Murray, William V. Journal of Medicinal Chemistry, 2005 , vol. 48, # 15 p. 4892 - 4909

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.22
  • LogP   3.8445
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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