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Structure of 406212-51-9
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1-tert-Butyl 3-methyl 4-hydroxypiperidine-1,3-dicarboxylate features a sterically hindered piperidine core with orthogonal functional handles: a bench-stable hydroxyl group and two ester moieties. This configuration enables selective derivatization in complex molecule synthesis, particularly in medicinal chemistry scaffolds requiring controlled polarity and metabolic stability.
1-tert-Butyl 3-methyl 4-hydroxypiperidine-1,3-dicarboxylate serves as a versatile chiral building block for the synthesis of piperidine-based pharmaceutical intermediates. The molecule features a protected hydroxyl group and two ester functionalities that enable selective derivatization, including reductive deprotection, nucleophilic substitution, and transition-metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard purification protocols make it well-suited for medicinal chemistry campaigns requiring stereocontrolled piperidine scaffold construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: