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CS-W001157 4
Total: USD 88.00

H-Tyr-OEt.HCl

  • CAS No. 4089-07-0

  • Cat. No. CS-W012709
  • Purity≥98%
  • MDL No.MFCD00063047

*For research and further manufacturing use only, not for direct human use.

H-Tyr-OEt.HCl|CS-W012709

Structure of 4089-07-0

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General Information

  • CAS No. 4089-07-0
  • Cat. No. CS-W012709
  • Purity ≥98%
  • MDL No. MFCD00063047
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO₃
  • Molecular Weight 245.70
  • Synonym(s) None
  • SMILES N[C@H](C(OCC)=O)CC1=CC=C(O)C=C1.Cl

Description

H-Tyr-OEt·HCl is a bench-stable, moisture-tolerant tyrosine derivative featuring a protected phenolic hydroxyl group and ethyl ester functionality. This form facilitates direct incorporation into peptide chains without side-chain modification, streamlining synthesis workflows in solid-phase and solution-phase peptide assembly.

Application

H-Tyr-OEt·HCl serves as a stable, bench-ready tyrosine derivative enabling efficient peptide synthesis and heterocyclic scaffold construction. The ethyl ester functionality facilitates straightforward derivatization and orthogonal protection strategies, while the hydrochloride salt ensures excellent solubility and handling stability. Functions reliably in standard coupling protocols and supports downstream modifications in medicinal chemistry workflows.

Synthesis

  • Route1
    • null|null
      64-17-5
    • L-Tyrosine Levodopa Impurity|CS-0229709
      60-18-4
    • ~97%
    • In-stock
      H-Tyr-OEt.HCl|CS-W012709
      4089-07-0

    References

    • Abarbri, Mohamed; Guignard, Alain; Lamant, Maurice Helvetica Chimica Acta, 1995 , vol. 78, p. 109 - 121 Title/Abstract Full Text Show Details Ousmer; Braun; Bavoux; Perrin; Ciufolini Journal of the American Chemical Society, 2001 , vol. 123, # 31 p. 7534 - 7538
  • Route2
    • null|null
      1634-04-4
    • L-Tyrosine Levodopa Impurity|CS-0229709
      60-18-4
    • ~%
    • In-stock
      H-Tyr-OEt.HCl|CS-W012709
      4089-07-0

    References

    • Ciba-Geigy Corporation Patent: US5506244 A1, 1996 ; US 5506244 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   1.2469
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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