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Structure of 4096-20-2
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N-Phenylpiperidine is a versatile heterocyclic scaffold featuring a phenyl ring directly linked to a piperidine core. This structure imparts enhanced lipophilicity and metabolic stability, enabling efficient membrane penetration. The compound serves as a key intermediate in medicinal chemistry, particularly for CNS-targeted therapeutics, where its balanced solubility and basic nitrogen facilitate target engagement.
N-Phenylpiperidine serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its stable piperidine core exhibits favorable functional group tolerance and facilitates diverse transformations, including alkylation, acylation, and transition-metal-catalyzed coupling reactions. The N-phenyl substitution enhances lipophilicity and modulates electronic properties, making it valuable for optimizing drug-like characteristics in CNS-targeted compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: