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Structure of 41292-65-3
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1H-Benzimidazol-5-ol features a fused benzene-imidazole core with a phenolic hydroxyl at the 5-position, conferring enhanced solubility and hydrogen-bonding capacity. This scaffold serves as a key pharmacophore in kinase inhibitors and fluorescent probes, offering stability under standard conditions and compatibility with diverse synthetic transformations.
1H-Benzimidazol-5-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its phenolic hydroxyl group facilitates direct functionalization and conjugation, while the imidazole core exhibits favorable solubility and stability under standard synthetic conditions. The compound functions effectively in coupling reactions and acts as a key intermediate in the synthesis of kinase inhibitors and other pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: