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Structure of 41337-83-1
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6-(Hydroxymethyl)picolinamide features a pyridine ring bearing both amide and hydroxymethyl functionalities, enabling versatile conjugation and solubility enhancement. This bifunctional scaffold integrates readily into peptide and small-molecule scaffolds, offering improved polarity and metabolic stability in bioactive compounds.
6-(Hydroxymethyl)picolinamide serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, offering a strategically positioned hydroxymethyl group adjacent to a pyridine nitrogen. It enables straightforward derivatization via oxidation, etherification, or nucleophilic substitution, while the amide functionality provides enhanced solubility and metabolic stability. The molecule exhibits excellent bench stability and is compatible with standard purification protocols, facilitating its use in multi-step synthetic sequences targeting bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: